The Cannabis plant has over 200 different terpenes, which are the chemical compounds giving each strain of Cannabis its unique smell. Caryophyllene is a primary terpene found in Cannabis, it is also heavily present in other plants like hops, clove, oregano, basil, and rosemary. It has a very strong, spicy aroma, similar to black pepper. Studies have shown that terpenes work alongside cannabinoids like CBD and THC to aid in their medicinal properties. Caryophyllene has been shown to bind to CB2 receptors in the body, which are usually found in and around the immune system, or around our internal organs. Because of this, Caryophyllene has been shown to be an anti-inflammatory and help with pain relief, which is why it tends to be present in many Cannabis topicals, also because of its strong scent. It has also been shown to help with anxiety, depression, and alcohol cravings. There has also been research done to see how terpenes can help fight cancer.
Beta-Caryophyllene has been studied with mice in recent years. In a 2015 study, this terpene was shown to stop the growth of tumors in mice suffering from melanoma, and it has also been shown to aid in the effectiveness of chemo treatments.
Certain strains of Cannabis contain high amounts of this terpene. Strains like Rockstar (a hybrid known for anxiety reducing and mood elevating effects), Skywalker (a hybrid with equal parts sativa and indica, known for body relaxation but not too sedative), or Super Silver Haze (a very popular sativa that promotes creativity) are very high in Caryophyllene and can be used to help with anxiety, muscle and joint pain, inflammation, etc.