ALS, otherwise known as amyotrophic lateral sclerosis (or more simply as Lou Gehrig’s Disease), is one of those rare neurological conditions with no known cure and for the most part, no known cause. It is defined as atrophy (withering away) of the muscles due to degeneration of the spinal cord nerves with which they attach.
Conventional therapeutic aids for ALS work by suppressing oxidative stress and inflammation while providing neuro-protectivity. CBD has all these properties and it can be used as a monotherapy or single administration drug for improving the symptoms of ALS. Several studies have shown that CBD has antioxidant, anti-inflammatory and neuroprotective benefits. It has been shown to have beneficial effects on all diseases involving the mitochondrial and basal ganglia portions of the brain. That means it can be used to prolong the survival of neuronal cells and to prevent worsening of the condition, if not its onset. In addition, CBD may help with other ALS symptoms through the promotion of bronchodilation and muscle relaxation as well as improving appetite and sleep.
In 2010, preclinical studies indicated that cannabis has powerful antioxidative, anti-inflammatory, and neuroprotective effects. In lab-mice, this led to prolonged neuronal cell survival, delayed onset, and slower progression of the disease. The lives of the mice were extended by six days, which translates into three years for humans. This 2010 lab study on mice also revealed that cannabis has symptom-reducing properties like pain relief (analgesia), muscle relaxation, bronchodilation, saliva reduction, appetite stimulation, and sleep induction etc. It is very common to treat pain with CBD and there is a lot of scientific and anecdotal evidence to back it up.
CBD: A Patients Guide To Medical Cannabis Book by Leonard Lenow & Juliana Birnbaum