Thyroid disorders can be caused by cancer, an excess or deficiency of iodine, infection and fluid build up, benign tumors or hormonal disorders. Cannabinoids may help with these issues. The thyroid is a gland that produces hormones which affect every single cell in our bodies, tissues and organs. It regulates our metabolic rate, cholesterol, heart, and bone and muscle function. Having an underactive thyroid gland causes HYPOTHYROIDISM, while an overactive gland causes HYPERTHYROIDISM.
Scientist have discovered there are cannabinoid receptors located on cells on the thyroid gland. There have also been receptors identified within the HYPOTHALAMIC PARAVENTRICULAR NUCLEUS (PVN), an area of the brain that send signals to the thyroid, regulating its activities. A 2009 study found the cannabinoid receptor type 1 (CB1) directly influences the activity of the neurons that control the thyroid.
The thyroid maintains constant communication with the brain via neural synapses, which regulate metabolism, heart rate, internal body temperature and emotional response. The ENDOCANNABINOID SYSTEM (ECS), which is present in both the central nervous system and the thyroid gland itself, plays a crucial role in proper communication.
In 2002 an animal study, published in the European Journal of Endocrinology, showed evidence that CB1 receptors regulate the release of thyroid hormones TRI-IODOTHYRONINE (T3) and THYROXINE (T4) and taking cannabinoids influenced hormonal activity. Evidence suggest CBD and other cannabinoids are beneficial in managing symptoms associated with thyroid disorders, ie. pain, depression, dry skin, inflammation and anxiety. This same study also showed a 30% decrease in hormone release within 4 hours of administering CBD.